Exercise-Regulated Vesicle Trafficking
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چکیده
منابع مشابه
Rab11 in Disease Progression
Membrane/ protein trafficking in the secretory/ biosynthetic and endocytic pathways is mediated by vesicles. Vesicle trafficking in eukaryotes is regulated by a class of small monomeric GTPases the Rab protein family. Rab proteins represent the largest branch of the Ras superfamily GTPases, and have been concerned in a variety of intracellular vesicle trafficking and different intracellular sig...
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To investigate the physiological function of the VAMP3 vesicle SNARE (v-SNARE) isoform in the regulation of GLUT4 vesicle trafficking, we generated homozygotic VAMP3 null mice by targeted gene disruption. The VAMP3 null mice had typical growth rate and weight gain, with normal maintenance of fasting serum glucose and insulin levels. Analysis of glucose disposal and insulin sensitivity demonstra...
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In eukaryotes, vesicle trafficking is regulated by the small monomeric GTPases of the Rab protein family. Rab11, (a subfamily of the Ypt/Rab gene family) an evolutionarily conserved, ubiquitously expressed subfamily of small monomeric Rab GTPases, has been implicated in regulating vesicular trafficking through the recycling of endosomal compartment. In an earlier communication, we have shown th...
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With the 2013 Nobel Prize awarded to scientists who uncovered mechanisms of vesicular trafficking, the next big question in the field is how this process is regulated. Talks in the Minisymposium on “Regulation of Vesicle Trafficking” highlighted ways in which GTPases from the highly conserved Ypt/Rab and Arf families regulate and coordinate vesicle trafficking steps. The roles of luminal phosph...
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تاریخ انتشار 2001